A.access-list 50 deny 192.168.1.1 0.0.0.255
B.access-list 110 permit ip any any
C.access-list 2500 deny tcp any host 192.168.1.1 eq 22
D.access-list 101 deny tcp any host 192.168.1.1

A.you can apply multiple access lists with the same protocol or in different direction.
B.you can config one access list,per direction,per layer 3 protocol
C.you can place as many access lists as you want on any interface
D.you can apply only one access list on any interface